Figure 2. MRI features suggestive of sCJD with slight progression of signal abnormalities. Short-term follow-up axial T2-weighted FLAIR images (a) show similar subtle cortical hyperintensities, again best appreciated in the right parietal cortex (grey arrow). Axial diffusion-weighted images (b) and apparent diffusion coefficient maps (c) show persistent and slightly more pronounced bilateral diffusion restriction in multiple cortical regions, caudate nuclei, and anterior putamina (white and black arrows).
Follow up awake EEG revealed pathologic diffuse slowing of background activity and bilateral periodic polyphasic sharp wave complexes, dominating in right frontal-temporal area (Figure 3).