Email:
killu.ammar@mayo.edu
Disclosures : None
Funding : None
Word count: 3746
(excluding references)
Abstract
Background: Data
regarding ventricular tachycardia ( VT) or premature ventricular
complex (PVC) ablation following MVS is limited.) CA can be challenging
given perivalvular substrate in the setting of mitral annuloplasty or
prosthetic valves.
Objective: To investigate the characteristics, safety, and
outcomes of radiofrequency catheter ablation (CA) in patients with prior
mitral valve surgery (MVS) and ventricular arrhythmias (VA).
Methods: We identified consecutive patients with prior MVS who
underwent CA for VT or PVC between January 2013- December 2018. We
investigated the mechanism of arrhythmia, ablation approach,
peri-operative complications, and outcomes.
Results: In our cohort of 31 patients (77% men, mean age
62.3±10.8 years, left ventricular ejection fraction 39.2±13.9%) with
prior MVS underwent CA (16 VT; 15 PVC). Access to the left ventricle was
via transseptal approach in 17 patients, and a retrograde aortic
approach was used in 13 patients. A combined transseptal and retrograde
aortic approach was used in one patient, and a percutaneous epicardial
approach was combined with trans-septal approach in 1patient.
Heterogenous scar regions were present in 94% of VT patients and
scar-related reentry was the dominant mechanism of VT. Clinical VA
substrates involved the peri-mitral area in 6 patients with VT and 5
patients with PVC ablation.
No procedure-related complications were reported. The overall
recurrence-free rate at 1-year was 72.2%; 67% in the VT group and 78%
in the PVC group. No arrhythmia-related death was documented on
long-term follow-up.
Conclusion : CA of VAs can be performed safely and effectively
in patients with MVS
Key Words : ventricular tachycardia, premature ventricular
complex, mitral valve, prosthesis