Statistical analysis
Continuous variables distributed normally were expressed as the mean ± standard deviation, and those with a skewed distribution were expressed as the median (interquartile range [IQR]). Categorical variables were expressed as frequency (percentage). For between-group comparisons, unpaired t-test was used for normally distributed variables, Mann-Whitney U test for non-normally distributed variables, and χ2 test (or Fisher exact test) for categorical variables. Kaplan-Meier methods were used to estimate survival or recurrence-free survival rates. The difference between patients with coronary artery diseases (CAD) and those without CAD was analyzed using the log-rank test. For all tests, a 2-tailed P-value <0.05 was considered statistically significant. All statistical analyses were performed using JMP Pro Software 14.3.0 (SAS Institute, Inc., Cary, North Carolina, USA) and GraphPad Prism 8.3.0 (GraphPad Software, La Jolla, California, USA).