Figure 5
Effect of the CYP genotype on the metabolic ratio (MR) of 4-MAA.The MR was calculated as (AUC12h 4-AA +
AUC12h 4-AAA + AUC12h
4-FAA)/AUC12h 4-MAA and the results displayed according
to the genotype of the different CYPs assessed. An increase in the MR
reflects an increase in the activity of a specific CYP. Individual data
are plotted.