Statistics
MR, AUC and 4-MAA t1/2 obtained for the ciprofloxacin,
fluconazole, and ciprofloxacin+fluconazole arms were compared to placebo
using the Wilcoxon signed rank test. Graphpad Prism (Graphpad Software,
La Jolla, California) was used for the statistical analysis. A Pvalue of <0.05 was considered as statistically significant
(*p<0.05, **p<0.01, ***p<0.001).