Fetal outcomes Number of studies Number of patients Proportion of event 95% CI
Congenital malformations
Treated group 28 7811 4% 0.03-0.04
Disease matched 10 29171 4% 0.03-0.05
Disease free 5 1251780 4% 0.03-0.05
Preterm Delivery
Treated group 26 7728 12% 0.10-0.14
Disease matched 11 18574 10% 0.09-0.12
Disease free 6 1626254 6% 0.04-0.07
General population WHO - - 9% 0.09-0.09
Neonatal Infection
Treated group 9 3554 5% 0.03-0.07
Disease matched 6 4015 5% 0.02-0.07
Disease free 2 14799 2% 0.02-0.02
Low Birth weight
Treated group 17 5112 10% 0.07-0.12
Disease matched 5 3046 8% 0.07-0.09
Disease free 4 3316 4% 0.01-0.08
Small for Gestational Age
Treated group 8 3342 6% 0.02-0.10
Disease matched 4 10720 7% 0.02-0.11
Disease free 4 1624533 10% 0.10-0.10