Observations:
Case 1: A 28-year-old male presented with multiple trichilemmal cysts of the scalp. Physical examination revealed, in addition, a thickened scalp with multiple symmetric skin folds from vertex to occipital area (figure 1). The systemic examination did not reveal any neurologic, ophthalmologic, or metabolic anomalies. Laboratory investigations were within the normal range limit. The diagnosis of primary essential CVG was retained and the patient required only excision of the cysts.
Case 2: A 32-year-old male with a history of epilepsy was referred to our consultation for a drug reaction secondary to phenobarbital. On examination, apart from the skin lesions consistent with the drug reaction, the patient had cerebriform folds on his forehead. The furrows were running horizontally and had a width of 1 to 2 cm (figure 2). He didn’t have any lesions on the scalp. No other anomalies were found. The diagnosis of primary non-essential CVG associated with epilepsy and involving only the forehead was retained.
Case 3: A 54-year-old female treated for hypertension, dyslipidemia, and a heart rhythm disorder, presented to our department with an occipital tumefaction evolving for a few years. The examination revealed cerebriform transverse occipital skin folds. The remaining physical examination was otherwise unremarkable. Given her chronic metabolic pathologies, secondary CVG was diagnosed.