Acknowledgments
We thank all the patients and healthy volunteers who agreed to
participate in the present study and all those who helped us
successfully complete the research.
This work was financially supported by Health Commission of Hunan
Province ( B2019138, Y.Y.), in part by Social Development Project of
Hunan Province Key Research Plan
(2020SK3044, J.H.), and Major
Scientific and Technological Projects for collaborative prevention and
control of birth defects in Hunan Province
(2019SK1010, G.H.). The funders had
no role in the study design, data collection and analysis, decision to
publish, or preparation of the manuscript.