Outcomes
We defined three outcomes for which we deemed that jointly would
adequately inform about unfavorable develompents in COVID-19
outpatients. COVID-19-related hospitalization – hospitalization
that followed within 45 days since the index COVID-19 diagnosis, with
U07.1/U07.2 as the leading discharge diagnosis; or hospitalization that
followed within 30 days since the index COVID-19 diagnosis and
U07.1/U07.2 is listed among discharge diagnoses. 30-day all-cause
hospitalization – hospitalization that follows within 30 days since
the index COVID-19 diagnosis. COVID-19-related death – we
considered that death was “related to” COVID-19 if meeting any of the
following (i) COVID-19 (U07.1/U07.2) is listed as a cause of death; (ii)
death occurred within 14 days since the index COVID-19 diagnosis,
regardless of the declared cause; (iii) death occurred in hospital,
where hospitalization was COVID-19 related hospitalization (as defined
above).