Unmatched/unadjusted Unmatched/unadjusted Unmatched/unadjusted Unmatched/unadjusted Unmatched/unadjusted Unmatched/unadjusted Unmatched/unadjusted Matched/adjusted1 Matched/adjusted1 Matched/adjusted1 Matched/adjusted1 Matched/adjusted1 Matched/adjusted1 Matched/adjusted1 Matched/adjusted1
Frequentist Frequentist Frequentist Bayesian Bayesian Bayesian Frequentist Frequentist Frequentist Bayesian Bayesian Bayesian Bayesian
GMR (95%CI) P GMR (95%CrI) P(GMR≠1.0); P GMR (95%CI) P GMR (95%CrI) P(GMR≠1.0); P
AUCτ,ss (mg•hr/L) 1.45 (1.10-1.92) 0.009 1.38 (1.07-1.81) 99.2%; 0.016 1.41 (1.11-1.79) 0.011 1.39 (1.05-1.81) 99.0%; 0.020
Cmax,ss (mg/L) 1.01 (0.71-1.44) 0.940 1.01 (0.74-1.39) 53.3%; 0.934 1.16 (0.80-1.68) 0.381 1.10 (0.78-1.52) 72.1%; 0.557
C0 (mg/L) 1.66 (0.99-2.79) 0.056 1.39 (0.91-2.11) 93.7%; 0.126 1.23 (0.62-2.41) 0.517 1.32 (0.86-2.08) 88.9%; 0.222
C12 (mg/L) 1.57 (0.88-2.81) 0.123 1.30 (0.84-2.06) 87.8%; 0.243 1.21 (0.60-2.41) 0.560 1.28 (0.81-2.06) 84.5%; 0.310
CLT/F,ss (mL/min/kg) 0.66 (0.48-0.90) 0.010 0.71 (0.53-0.95) 98.9%; 0.022 0.73 (0.58-0.93) 0.016 0.71 (0.54-0.95) 98.8%; 0.024
Cmax/AUCτ (1/h) 0.70 (0.50-0.96) 0.029 0.75 (0.55-0.99) 97.5%; 0.050 0.81 (0.57-1.14) 0.193 0.81 (0.60-1.15) 89.6%; 0.208