Results
Six patients were included in this study, with an average age of 59 (range [48-67]). Demographics and tumor characteristics are included in Table 1. Notably, all patients were Caucasian and male. Primary tumor sites included tonsil (2/6), tongue base (1/6), and glossotonsillar sulcus (3/6).
System 1 showed poor tumor-margin definition with no fluorescence in 4 of 6 cases (66.7%) and only minimal fluorescence in the remaining 2 cases (33.3%) (Fig. 1). In contrast, System 2 showed marked fluorescence in 5 of 6 cases (83.3%), with good definition of margins in 4 cases. In two cases, the oropharyngeal lesion was poorly visualized by the surgeon in vivo , but showed marked ICG fluorescence when visualized using System 2 (Fig. 2).