Summary
COVID-19 is a major challenge of public health in the globe, which has seriously endangered human health and safety, affected people’s daily study, work and life, and halted the world’s economic and social development. The pandemic in many countries, regions or locals is still continuing. Current status is still serious due to the Delta and Omicron variants and it’s also a high risk factor of cardiovascular health. The “ISISI” barriers based on these comprehensive strategies will help us to combat the SARS-CoV-2 and its variants during the pandemic and post-COVID-19 era, protect cardiovascular health, and get final victory from effective vaccination.