\documentclass[10pt]{article}

\usepackage{fullpage}
\usepackage{setspace}
\usepackage{parskip}
\usepackage{titlesec}
\usepackage[section]{placeins}
\usepackage{xcolor}
\usepackage{breakcites}
\usepackage{lineno}
\usepackage{hyphenat}





\PassOptionsToPackage{hyphens}{url}
\usepackage[colorlinks = true,
            linkcolor = blue,
            urlcolor  = blue,
            citecolor = blue,
            anchorcolor = blue]{hyperref}
\usepackage{etoolbox}
\makeatletter
\patchcmd\@combinedblfloats{\box\@outputbox}{\unvbox\@outputbox}{}{%
  \errmessage{\noexpand\@combinedblfloats could not be patched}%
}%
\makeatother


\usepackage{natbib}




\renewenvironment{abstract}
  {{\bfseries\noindent{\abstractname}\par\nobreak}\footnotesize}
  {\bigskip}

\titlespacing{\section}{0pt}{*3}{*1}
\titlespacing{\subsection}{0pt}{*2}{*0.5}
\titlespacing{\subsubsection}{0pt}{*1.5}{0pt}


\usepackage{authblk}


\usepackage{graphicx}
\usepackage[space]{grffile}
\usepackage{latexsym}
\usepackage{textcomp}
\usepackage{longtable}
\usepackage{tabulary}
\usepackage{booktabs,array,multirow}
\usepackage{amsfonts,amsmath,amssymb}
\providecommand\citet{\cite}
\providecommand\citep{\cite}
\providecommand\citealt{\cite}
% You can conditionalize code for latexml or normal latex using this.
\newif\iflatexml\latexmlfalse
\providecommand{\tightlist}{\setlength{\itemsep}{0pt}\setlength{\parskip}{0pt}}%

\AtBeginDocument{\DeclareGraphicsExtensions{.pdf,.PDF,.eps,.EPS,.png,.PNG,.tif,.TIF,.jpg,.JPG,.jpeg,.JPEG}}

\usepackage[utf8]{inputenc}
\usepackage[english]{babel}



\usepackage{float}








\begin{document}

\title{A novel comprehensive program combined optimal medical treatment and
lifestyle for type 2 diabetes}



\author[1]{Chunsong Hu}%
\author[2]{Tengiz Tkebuchava}%
\author[3]{Qinghua Wu}%
\affil[1]{Nanchang University}%
\affil[2]{Office of the President/CEO, Boston TransTec, LLC, Boston}%
\affil[3]{Department of Cardiology, the Second Affiliated Hospital of Nanchang University}%


\vspace{-1em}



  
  \date{June 15, 2024}


\begingroup
\let\center\flushleft
\let\endcenter\endflushleft
\maketitle
\endgroup





\selectlanguage{english}
\begin{abstract}
This article introduces briefly current status in managing type 2
diabetes (T2D) and an updated classical standardized comprehensive
program which combines optimal medical treatment (OMT) with lifestyle
modification, that is, intervention of RT-ABCDEFG (iRT-ABCDEFG) for
control and prevention of T2D, and discusses its advantages and
prospects. Here, G means goals; F means follow-up; E means examination;
D means disease \& risk factors control; C means changing unhealthy
``environment-sleep-emotion-exercise-diet'' intervention {[}E(e)SEEDi{]}
lifestyle \& Chinese medicine or control the source of infection \&
cutting genetic or spreading pathways during the COVID-19 pandemic; B
means biohazard control; And A means antagonistic treatment, such as
optimal anti-diabetic agents, the glucagon-like peptide-1 receptor
(GLPR) agonists, the sodium-glucose cotransporter 2 (SGLT2) inhibitors,
and the ultralong-acting, once-daily basal insulin. As a novel strategy
for Intervention of diabetes, this program can be used as a Reverse,
Right, and Routine Treatment in clinical practice. Moreover, the vital
goals which include less major adverse cardiocerebrovascular events
(MACCE) and diabetic complications, less medical costs, longer life
expectancy, lower morbidity and mortality, and higher quality of life,
will be realized by consistently practicing this program due to early
diagnosis, OMT, and overall prevention. Whatever, this program is very
helpful to manage or self-manage T2D and improve its outcomes since it
highly links to cardiovascular disease (CVD), stroke, cancer, and other
MACCEs.%
\end{abstract}%



\sloppy


\textbf{Hosted file}

\verb`20211015 T2D.doc`  available at \url{https://authorea.com/users/443069/articles/712181-a-novel-comprehensive-program-combined-optimal-medical-treatment-and-lifestyle-for-type-2-diabetes}

\selectlanguage{english}
\FloatBarrier
\end{document}

