Limitations
This retrospective analysis relied on the assumption that all EGMs would
have been reviewed, and the EGM review burden could be directly
quantified by the number of EGMs presented on the patient care network.
Prospective studies are needed to demonstrate the real-world impact of
key EGM selection on clinical review burden.
All TP episodes were assumed to be diagnostically equivalent for
calculations of diagnostic delay, with the earliest possible diagnosis
of each patient occurring on the first day a TP EGM was recorded. In a
real-world clinic, a single EGM snapshot of one true arrhythmia episode
may not be sufficient for a definitive diagnosis, as its diagnostic
value is subjective and may vary among clinicians. However, by
quantifying the time-to-diagnosis using key EGMs relative to all
recorded EGMs, and doing so across a random population, any qualitative
differences in diagnostic value are not expected to significantly alter
the conclusions.