Introduction
A COVID-19 catastrophic infection crisis, driven by the new coronavirus
SARS-CoV-2, has presented a grave threat around the world. Bangladesh
has also been affected by this viral infection(1). The World Health
Organization labeled it a pandemic based to its parabolic spread in 213
nations (2). The disease is spread mostly through direct contact with
infected patients’ airborne droplets(3). To minimize the spread of
disease, rapid recognition and accurate diagnosis have become critical.
Several samples, such as nasopharyngeal or oropharyngeal swabs,
nasopharyngeal or oropharyngeal aspirates or washes, bronchoalveolar
lavage, phlegm, tracheal swab and blood, are collected from potential
SARS-CoV-2 patients. The microbiological diagnosis is confirmed using
the polymerase chain reaction (PCR)(4). SARS-CoV-2 RNA virus load in the
upper airways was considerably higher throughout the first week and
culminated at 4-6 days following onset of symptoms, when it could be
sampled. In COVID-19 individuals, the sensitivity of nasopharyngeal
scrapes was higher than that of oropharyngeal sweeps(5). But even though
the research on COVID-19 is inconclusive, lower respiratory tract
tissues include the highest viral loads in individuals with severe acute
respiratory syndrome (SARS) and Middle East respiratory disease
(MERS)(6, 7). Nucleic acid screening for severe acute respiratory
syndrome coronavirus 2 had also detected benign patients with
coronavirus infection (SARS-CoV-2)(8).In this report, we have presented
a case of persistent COVID-19 negative report of physician in Bangladesh
living and visiting in Red listed country.