We, the authors of the manuscript titled ’Actinomyces in Hand: An Unusual Cause of Osteomyelitis,’ are currently studying and conducting research at Imam Khomeini Hospital in Tehran, Iran. We would like to clarify that this article is entirely personal and we are not representing any governmental entity. Our research and academic activities are carried out independently and are not associated with any sanctioned government body. We kindly request that you consider this clarification in the processing of our manuscript.
Abstract:
actinomycosis is a chronic and invasive condition caused by Actinomyces bacteria. It is crucial to diagnose and treat the infection promptly to prevent complications and ensure favorable outcomes for patients. In this case, the 82-year-old man initially presented with pustules on the dorsal side of his left hand, which eventually led to the biopsy that revealed the characteristic histopathologic features of actinomycosis. The subsequent imaging studies further confirmed the extent of the infection, showing osteomyelitis in the carpal bones and proximal metacarpals, along with joint destruction and multiple collections. Treatment with intramuscular ceftriaxone was attempted, but unfortunately, it proved ineffective in this particular case. However, with the suspicion of mycetoma and eumycetomas based on the biopsy findings and imaging results, a culture was performed to detect the microbial organism. The subsequent histologic evaluation confirmed the diagnosis of actinomycosis, providing valuable information for selecting appropriate antibiotics.
It is important to note that delays in diagnosis or aggressive disease spread can lead to severe complications and even fatal outcomes. Therefore, accurately identifying and isolating the infecting bacteria through culture and pathology are vital steps in the diagnostic process.
Overall, this case emphasizes the significance of a multidisciplinary approach involving pathology, imaging, and microbiology to diagnose and manage actinomycosis effectively.
Keywords: Actinomycosis, Chronic, Biopsy, Osteomyelitis, Antibiotics