Integrating absorption, delayed opening of the collection chamber, and docking control into a single device could potentially enable the isolation of biomarkers within the hard-to-access regions of the body, as shown in schematic illustrating the retention of a robotic pill in the small intestine through magnetic retention (Figure 1b). In addition, the pill was designed to be comparable to FDA-approved ingestible device standards, as its measurements are 16 mm in length, 6 mm in diameter and 1.5 mm in thickness. [30] (Figure 1c). The sampling capability of the pill is illustrated by Figure 1d, where the photographs show a robotic pill before (top) and after (bottom) immersion (5 min) in water colored in blue dye, where each of the three collection chambers retained the liquid captured by the absorbent material.