not-yet-known not-yet-known not-yet-known unknown
Table S8: Resection of relapsed disease compared to No resection for Rhabdomyosarcoma
Patient or population: RhabdomyosarcomaIntervention: Resection of relapsed diseaseComparison: No resection
Outcomes № of participants
(studies)
Follow-up Certainty of the evidence
(GRADE) Relative effect
(95% CI) Anticipated absolute effects
Risk with No resection Risk difference with Resection of relapsed disease
Mortality 446(6 non-randomized studies)53-59 ⨁○○○Very lowa,b OR 0.15(0.06 to 0.39) 126 per 1,000 105 fewer per 1,000(118 fewer to 73 fewer)
*The risk in the intervention group (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI).CI: confidence interval; OR: odds ratio
GRADE Working Group grades of evidenceHigh certainty: we are very confident that the true effect lies close to that of the estimate of the effect.Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different.Low certainty: our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect.Very low certainty: we have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect.