Strengths and limitations
The strengths of the study lay in its prospective design, the large sample size with statistical justification, and evaluation of several antibodies against SARS-CoV-2. The limitations of the study were the lack of serial maternal serology sampling, insufficient sample size for assessing neonatal complications related to COVID-19 and parental refusal to allow neonatal SARS-CoV-2 nasopharyngeal swabbing. It should be noted that only five neonates were born within 2 weeks of maternal SARS-CoV-2 infection, when serology test sensitivity and specificity might be lower.