Introduction
Collodion phenotype is a common clinical presentation of a heterogeneous group of skin disorders of cornification. The term collodion baby (CB) was firstly introduced by Hallopeau and Watelet describing a parchment-like membrane that covers the whole body.1Is a rare clinical entitywith an estimated incidence of 1 in 50.000 to 100.000 live births. Collodion phenotype is common to several different forms of autosomal recessive congenital ichthyoses including lamellar ichthyosis, nonbullous congenital ichthyosiform erythroderma, and harlequin ichthyosis. 2,3 The diagnosis of CB is clinical as the skin biopsy and histopathology in the first few weeks of life will not be useful in differentiating different types of ichthyosis. In recent years considerable advances in the understanding of the molecular basis of congenital ichthyosis were made identifying several genes implication in the pathogenesis. Management of CB remains a challenge in the neonatal period as the complications occur in almost half of the patients with a mortality rate of approximately 11% in the first weeks of life. 4We report a unique case of self-healing CB that was managed successfully despite the risk of potentially serious complications. Self-healing CB is a rare and distinct outcome of collodion phenotype occurring in approximately 10% of all collodion babies.