Outcomes of CF Hospitalizations with and without co-existing diagnosis of C. difficile
In-Hospital Mortality
The overall mortality among CF hospitalizations with CDI was 3% compared to <1% among CF hospitalizations without CDI (P<0.001) (Table 1.2). Upon multivariate analysis, the odds of mortality among CF hospitalizations with C. difficile infection was 5.2 times that of pediatric CF hospitalizations without C. difficile (95% CI: 2.5-10.7)(Table 1.3).
Length of Admission
Overall median length of stay was 10 days among CF hospitalizations with CDI compared to 7 days among CF hospitalizations without CDI (p<0.001) (Table 1.2). After adjustment, the length of stay for CF hospitalizations with CDI was 46.5% longer than CF hospitalizations without CDI (95% CI: 36.0-57.1) (Table 1.3).
Health Care Expenditure
Overall median hospital charges (in USD) were 41,842 among pediatric CFC. difficile hospitalizations compared to 23,806 among non-C. difficile hospitalizations (P<0.001) (Table 1.2). After adjustment, hospital charges among C. difficile CF hospitalization were 65.8% more than the for non-C. difficilehospitalizations (95% CI: 53.5-78.1)(Table 1.3).