Signs and Symptoms at initial onset and at diagnosis
The average number of symptoms is 1.7 at onset and 1.9 at diagnosis (Table 1). Vomiting and headache were the most common symptom at onset and diagnosis, with 62% of all patients showed signs of vomiting. 44% of patients exhibited with motor problems, with the most common symptom being abnormal gait (35%) and focal motor weakness (15%.) Visual problems were seen in 26% of all patients at diagnosis, with the most common symptom being reduced acuity (14%) and abnormal eye movements (7%.) Only 2% of all patients exhibited weight loss. The most common behavioural problems were lethargy, reported in 5% of patients.