In Figure 9a, combinations that improved the %Yield of red spinach were highlighted. Notably, the 1st ranked combination (6-BAP/Adenine/EDTA-Fe) failed to demonstrate any apparent effect in %Yield (-3.60±11.70) even though it was ranked first among all possible combinations. This can be explained by concentration-dependent interactions observed in Figure 9b, 9c, and 9d, which illustrated the response surfaces of all interactions of 6-BAP/Adenine/EDTA-Fe. Though these surfaces may not have strong correlations to explain the relationship between input compounds and the %Yield of plants, they did however provide insight into the response of red spinach growth to the input compounds. Within the dotted black box outlining the WisDM Green-assessed concentrations (0 – Level 2), Adenine/EDTA-Fe and Adenine/6-BAP exhibited slight antagonistic effects and concentration-dependent interactions, which can potentially explain the reason why 6-BAP/Adenine/EDTA-Fe had no effect in %Yield in that range (Figure 9b and 9d). The observed concentration-dependent interactions implied that adjusting the concentration ratios of 6-BAP/Adenine/EDTA-Fe may potentially increase the %Yield. Subsequent interrogation of compound interaction demonstrated that adjusting concentration-dependent ratios may markedly enhance %Yield.  Of note, the 2nd ranked combination (6-BAP/HA/SWE/Starch) demonstrated an increase in %Yield (15.32±8.42).