Background:
COVID-19 is a leading cause of morbidity and mortality worldwide. Apart from the respiratory complications which are responsible for most of the deaths, several serious complications have been reported including compressive emphysema or acute pancreatitis. COVID-19 can also induce a hypercoagulable state, at the origin of venous and arterial thromboembolic events. This hypercoagulability is associated with high morbidity and mortality [1,2]. The literature mainly describes venous thromboembolic events and pulmonary embolisms [3,4]. Arterial thrombosis during COVID-19 is poorly described compared to venous thrombosis. According to literature, it can occur with a prevalence of 0.13% in a hospitalized patient who tested positive for COVID-19 and 0.19% in patients who tested negative [5]. We report a case of an extensive arterial thrombosis with extremely high D-dimer level that resulted in a lower limb ischemia in a COVID-19 patient.