Contribution of authorship
DK, SAN, and MVZ contributed to the design and conception of the study,
and obtained funding. JP, DK and SH developed the imaging protocol for
placental tissue. Sample preparation and imaging was performed by JP,
and SH. The MATLAB extension KnotMiner was built by JS and DE. DE
trained and employed Stardist for nuclei segmentation. Methods for image
quantification and data analysis were established by SH and DK. SH and
DK drafted the manuscript. JP, DE, JS, SAN, CS and MVZ read, contributed
to manuscript revision, and approved the submitted version.