Conclusion
Our results demonstrated MPM to be a suitable method to visualize placental tissue and the processing methodology developed can quantifiably differentiate placental morphologies. This methodology could be further utilised to phenotype PE subtypes, and ultimately aid in unravelling the multi-etiological nature of preeclampsia. In the future, stratification based on 3D placental morphology could aid in the search for early diagnostic markers and (preventative) treatment options to improve maternal and foetal outcomes.