Results
One hundred and eighteen volunteers were eligible for this study, of
them 22 excluded due to the lack of understanding the execution of some
of the tests. In total, 96 volunteers were evaluated, with the sickle
SCAG consisting of 48 volunteers (56% female) with mean age of 13 ± 3
years. The characteristics of the volunteers are described inTable 1 .
Spirometric values of the SCAG were worse when compared to the CG (p
<0.05). Regarding respiratory muscle strength, there was
difference between groups with lower MEP values in the SCAG compared to
the CG, p = 0.03 (Table 2 ).
The SCAG spent more time to perform 5STS-test, 8 seconds (7-9 seconds),
compared to the CG, 7 seconds (7-8 seconds), p < 0.001.
Similar result was observed at the MST, which distance walked was
shorter at SCAG 576m (515-672m), compared to the CG, 1010m (887-1219m),
p < 0.001 (Table 2 ).
The SCAG had poorer quality of life scores than the CG according to the
Pedsql TM4.0 domains: physical functioning 66 (59 -
74) vs 94 (79 - 97), emotional functioning 65 (50 - 80) vs 75 (60 - 89),
social functioning 80 (66 - 94) vs 95 (81 - 100) and school functioning
50 (40 - 70) vs 87 (74 - 91), p <0.05.
To test the reproducibility between the SCAG functional capacity tests,
the outcomes were compared between test and retest. The ICC was
excellent between the two MSWT: 0.99 (0.98-0.99 IC-95%) p
<0.001. The Bland-Altman analysis showed bias of -1.6m ( -42m
- 39m) were observed (Figure 1A ). Similar results were observed
at 5STS-test with an excellent ICC: 0.8 (0.7 – 0.9) p <0.001.
The Bland Altman’s analysis showed bias of 0.36 seconds was observed
(-2.6 - 3.3 seconds) (Figure 1B ).