Category N Model 1 a P-value* Model 2 b P-value*
Concentration divided on median 93 0.91 (0.54-1.55) 0.74 1.10 (0.63-1.94) 0.73
Concentrations below LLQ 10 Ref. 0.61
Lowest tertile 26 1.59 (0.62-4.07) 0.33 -
Middle tertile 29 1.16 (0.44-3.01) 0.77 -
Highest tertile 28 1.05 (0.41-2.69) 0.92 -
Z-score 93 0.96 (0.72-1.27) 0.76 1.09 (0.79-1.52) 0.59
Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05 Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05 Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05 Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05 Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05 Data is presented in Hazard Ratio with 95% confidence interval. N = number of plasma concentration. Number of events=57 a Model 1: adjusted for age and gender. b Model 2 of median concentration and z-score adjusted for DDD, other covariates did not influence the model. Model 2 of category percentiles was not applied considering the limited amount of events. *statistically significant at p<0.05