5. CONCLUSION
Determination of IMA and thiol/disulfide homeostasis levels, which are
predictive of postoperative complications in on-pump CABG, is important
for the success of the surgical procedure and the prognosis of the
disease. Redox hemostasis, which is disrupted by the surgical procedure,
cardioplegia application, perfusion technique, blood pressure change,
non-endothelial surface and anesthesia applications in the on-pump CABG
process cause many secondary complications. In the on-pump CABG, cardiac
damage can be minimized by making therapeutic supplements with
antioxidant properties to the thiol/disulfide balance or by developing
biocompatible surfaces.