5. CONCLUSION
Determination of IMA and thiol/disulfide homeostasis levels, which are predictive of postoperative complications in on-pump CABG, is important for the success of the surgical procedure and the prognosis of the disease. Redox hemostasis, which is disrupted by the surgical procedure, cardioplegia application, perfusion technique, blood pressure change, non-endothelial surface and anesthesia applications in the on-pump CABG process cause many secondary complications. In the on-pump CABG, cardiac damage can be minimized by making therapeutic supplements with antioxidant properties to the thiol/disulfide balance or by developing biocompatible surfaces.