Abbreviations : ICI: immune checkpoint inhibition; SBRT:
stereotactic body radiotherapy
Figure 1 : Partial Response in Patient Receiving ICI + SBRT.
83-year-old man with right temporal WHO grade IV glioblastoma
status-post resection and adjuvant concurrent radiotherapy and
temozolomide who received 30 Gy in 5 fractions concurrently with 15
cycles of ICI as his third line treatment. Radiotherapy isodose line
key shown in (A). Representative (B) axial (C) sagittal and (D) coronal
images of his RT plan. Pretreatment MRI (E) axial T1 and (F) axial T2
FLAIR showing 2 x 2.1 cm nodular enhancing mass along anterior/medial
margin of the resection cavity. MRI 4 months post-SBRT (G) axial T1 and
(H) axial T2 FLAIR showing overall decrease in size and nodular
enhancing component of the lesion
Figure 2: Kaplan-Meier curves for (A) progression free survival
and (B) overall survival time. Dashed lines are 95% confidence
intervals