Funding Statement
This study was supported by the Key Research and Development Plan of Hainan Province (grant No. ZDYF2022SHFZ085); Hainan Provincial Natural Science Foundation of China (grant No. 823RC598, 820QN267, 821QN258, 821QN0896, 821QN262, G20230324004Y and 821RC1070), the National Natural Science Foundation of China (grant No. 82360658, 82060378), the Innovative Scientific Research Project of postgraduates in Hainan Province (grant No. HYYS2021A17, Qhys2021-356, Qhys2021-352, Qhys2023-487 and Qhyb2023-176), and the Hainan Province Clinical Medical Center (QWYH202175). The funding sources had no role in the study design, data collection, analysis, interpretation, or writing of this report.