3.5 Impact of RV genotypes on severity of respiratory
infections
To explore the relationship between RV subtypes and clinical
characteristics, clinical information from the 32 patients with
identified subtypes was analyzed (Table 4). Eight patient was diagnosed
with asthma among the 32 patients. RV-C was found to be the predominant
species in asthma patients, accounting for 50% (4/8) of asthma cases,
followed by RV-A for 37.5%(3/8), and RV-B for 12.5%(1/8). There was no
significant difference among the positive rate of asthma cases in the
group of patients with the same RV species (p =0.667).
In this study, the 32 patients were further divided into non-severe and
severe lower respiratory tract infection (LRTI) categories. There was no
significant age differences observed between the groups (Table 4). Males
demonstrated a higher prevalence of severe RV-associated LRTIs,
accounting for 85.71% of severe cases. Asthmatic children showed a
greater susceptibility to severe LRTIs and extended hospitalizations,
suggesting that asthma may elevate the risk of intensified infections in
those with RV.