Abstract
Background: As the COVID-19 pandemic evolves, many pediatricians and
infants’ parents have been left with renewed questions about the
consequences of infection on children and steps to be taken if their
child has symptoms of, or tests positive for, COVID-19. Methods &
Results: Literature reviews and recent studies revealed that children
are better than adults at combating SARS –CoV‑2. There was conflicting
evidence on age-related differences in ACE2 expression in the nose and
lungs. However, measurements of SARS-CoV-2 viral load’ have shown no
clear difference. Strikingly, cross-reactive antibodies from previous
exposure to coronavirus common cold do not offer any special protection
in both children and adults. The kid’s immune response against SARS‑
CoV-2 infection is initiated with low immunological tone to prevent
overactive immunity and is characterized by rapid lung damage repair in
contrast to stormy waves in adults. Conclusion: One of the few silver
linings of the COVID-19 pandemic is that children are relatively spared
and wining with their immunity.