Exploration of suspected adverse drug reactions (Loose motion and
Diarrhea) of Dapagliflozin during the treatment of type-2diabetes
mellitus: A Case Report
Abstract
Objective: The objective of present clinical report was to highlight
importance of early identification of adverse drug reactions (ADRs) in
the patients who have taken dapagliflozin during the treatment of type-2
diabetes. Case presentation: A 58years old female patient having body
weight 49 kg, a known case of type-2 diabetes (Since 8 years) visited
the outpatient department at the tertiary care hospital on 1st June,
2022, with the complaints of uncontrolled diabetes (since 3 year) along
with lower limb pain . Patient was evaluated, investigated by the
consultant .After taking of medication patient started loose motion/
diarrhea 8- 10 episodes on 2nd June, 2022. The risk of developing loose
motion/diarrhea while taking of dapagliflozin with certain factors such
as advance age, drug- drug interaction, genetic polymorphism and gender.
Conclusion: This case highlights the need of monitoring of dapagliflozin
treatment in clinics and hospitals. The use of risk stratification tool
to identify the risk of patients and also need for self monitoring by
the patients.