Analysis of Prescribing Patterns and Adverse Drugs Reactions in Diabetic
Patients at Tertiary Care Hospital, Lucknow
Abstract
Objective: To study the prescribing pattern and adverse drug reactions
(ADRs) of anti-diabetic drugs in a tertiary care hospital in Lucknow,
India. Methods: A prospective study was conducted over a period of 6
months at the inpatient and outpatient departments of the hospital. A
total of 100 patients with diabetes were included in our study.
Demographic characteristics were recorded and 100 prescriptions were
analyzed. ADRs were reported and analyzed. Results: Among the 100
patients, 58 were male and 42 were female. The majority of the patients
were in the age group of 41-60 years. Biguanides (38%) and
sulphonylureas (31%) were the most commonly prescribed anti-diabetic
drugs. A total of 8 ADRs were reported, including hypoglycemia, gastric
irritation, and abdominal discomfort. Metformin had the highest number
of ADRs among the oral hypoglycemic drugs. Conclusion: The study showed
that the prescribing pattern of anti-diabetic drugs in the hospital was
in line with the essential medicine list. ADRs were reported, with
hypoglycemia being the most common ADR observed. Continuous monitoring
and reporting of ADRs is necessary for the safe and effective use of
anti-diabetic drugs. Keywords: Prescribing pattern, adverse drug
reactions, anti-diabetic drugs, diabetes, metformin