Mice
Male DBA/1J mice, 8-10 weeks old) were purchased from Changzhou Cavens Laboratory Animal Co., Ltd. Mice were housed in specific pathogen–free conditions under controlled conditions of 12-hour light/12-hour dark and with food and water ad libitum at 25°C. All experimental protocols were approved by the Ethics Committee for Animal Research of the Affiliated Drum Tower Hospital of the Nanjing University Medical School.