RSV genotypes
Phylogenetic analysis of 116 sequenced RSV isolates showed that 51 RSV-A (9 from 2021 and 42 from 2022) viruses belong to the ON1 /genotype and 65 RSV-B (24 from 2021 and 41 from 2022) viruses belong to BA9 (Figure S1).
The ON1 was divided into two major clades and four small clades. The first major clades were related to strains from Kenia 2015, France 2021 and USA 2022 (30 patients), and the second to Netherlands 2021, Slovenia 2021 and France 2022 (15 patients). The small clades were related to strains from Bangladesh 2012 (1 patient), China 2018 (1 patient), Slovenia 2021(1 patients), USA 2022 (3 patients) (Figure 2A).
The BA9 was divided in one major clade related to strains from China 2019, Japan 2019, Italy 2021, USA 2021 Australia 2022, and Austria 2022 (22 patients 2021/ 41 patients 2022), and in two small clades all of 2021 related to strains from Germany 2017, Spain 2018, Thailand 2019 and China 2020 (1 patient), China 2021(1 patient) (Figure 2B).