Correlation between Histology and Reflectance Confocal Microscopy
Histology shows irregular epidermal hyperplasia overlying a dermal nodule composed of round bluish and vacuolated cells surrounded by dermal fibrosis, telangiectasia and chronic inflammation. RCM shows hyperplastic polycyclic loops representing dermal epidermal junction overlying a central hyperreflective homogenous area composed of dermal fibrosis, telangiectasia and chronic inflammation (correlating with histopathology) and a lobule in the center of the lesion (Figure 2 and 3 ).