5. Conclusions
Self-assembly is a highly efficient procedure for active enzyme encapsulation. The VLP-encapsulated GOx enzyme showed significant catalytic activity. The nanoreactors containing GOx activity are entirely suitable for cytotoxicity generation in tumor cells. The HSA functionalization of the VLP-GOx nanoreactors could result in a prevailing strategy to improve selective cancer targeting. The GOx containing enzymatic nanoreactors seems to be an efficient alternative to improve the current cancer therapy. In vivo studies are envisaged to reinforce the effectiveness of this treatment strategy.