DISCUSSION
PG is an uncommon kind of inflammatory skin disease that is not caused by an infection and is characterized by painful necrotic ulcers that often appear on the legs(6). It is believed that PG is an autoimmune disease; however, the exact cause of the disease is not completely known.
Although PG is frequently linked with systemic conditions such as inflammatory bowel disease, rheumatoid arthritis, and hematologic malignancies, the incidence of PG as a prior symptom of SLE is very uncommon and has only been described in a few individuals to this point(7).
The identification of PG is established through the process of excluding other potential sources of cutaneous ulcerations that present with similar characteristics, such as infections, cancers, vasculitides, venous insufficiencies, and trauma(8).
To date, in the majority of cases that have been documented, before the manifestation of PG symptoms, a diagnosis of SLE was made. H. B. Kwon et al. delineated the clinical manifestation of PG in a female patient aged 35 years, who exhibited the characteristic symptom of painful ulcers on her lower extremities as our case. The subsequent assessment indicated that the patient also presented with SLE, posited as the fundamental etiology of her dermatological manifestation. They deliberate on the plausible mechanisms that connect the two aforementioned conditions and underscore the significance of prompt identification and intervention(9).
In another case study, S. N. Jha et al. demonstrated a female patient, aged 30 years, diagnosed with SLE, presented with PG affecting her lower limbs. The authors delve into the plausible immunological mechanisms that underlie this correlation and emphasize the significance of interdisciplinary administration(10).