Study Approval
Blood donors signed an informed consent in accordance with the D.M. November 2nd 2015 entitled ”Provisions relating to the quality and safety requirements of blood components”. In accordance with the ministerial provisions and the IOG 364 institutional procedure ”Request and delivery of buffy coats for research purposes”, it is not possible to retrieve any type of information (gender, age, HLA typing) of donors. The animal study protocol was approved by the local animal ethics committee of San Raffaele Hospital (IACUC n 532/2022-PR, approved September 12, 2022).