Massenger RNA (mRNA) expression studies of SULT1E1
When administered for a period of 7 days, it was discovered that DAS and Chalcone, both alone and collectively, were able to increase mRNA in comparison to the animals in the control group via inducing transcription of the SULT1E1 gene. SULT1E1 mRNA was highly expressed in the DAS treated cells. Chalcone also expresses SULT1E1 mRNA but less than DAS. Whereas DAS+Chal treated showed highest SULT1E1 in comparison to DAS alone and Chalcone alone group but a single animal had low SULT1E1 mRNA. These expressions were all higher than the control group (Fig-4c).