SULT1E1 protein expression in Tumor and surrounding tissues
Expression of SULT1E1 protein in tumour was comparatively higher than
corresponding surrounding tissues. A few surrounding tissue have shown
an increased SULT1E1 expression, whose corresponding tumor shows more
intense SULT1E1 expression. Our findings abide by earlier study that
suggests that SULT1E1 is expressed more in the tumor tissues as compared
to their surroundings, and our studydid the first attempt to explain
that, though SULT1E1 is overexpressed in tumor it remains inactive (28).
Considering both the studieswe utilized DAS and Chalcone separately as
SULT1E1 inducer and reducing agent and also in combination to mainatian
an elevated active SULT1E1 state.