Chemotherapy vs. HSCT
Thirteen patients went on to receive stem cell transplant form fully
matched, HLA identical health siblings as donors, while chemotherapy
alone was administered in rest of the patients . From the transplanted
group of patients all of them achieved full-engraftment, however four
patients relapsed, while three patients died in remission due to
toxicity related to the transplant and could be characterised as
transplant related mortality. Out of the 18 patients who received
chemotherapy, four patients have relapsed, while 11 patients died due to
treatment – related toxicities. When comparing OS at 3 -years who
proceeded to receive HSCT vs. chemotherapy (61.4% vs. 27.3%) no
statistical significance was observed as demonstrated in Figure 2