Figure 7 Concentration of 5-HT and CORT in serum
Note: *P <0.05 and **P <0.01 compared with the CON+NS group;#P <0.05 and##P <0.01 compared with the MS+NS group.
3.2.4. Probiotics on hippocampal 5-HT and cAMP/CREB signaling pathways in mother-infant isolated offspring of depressed-like rats
(1) The immunohistochemical microscopic results showed that in the hippocampal region, the cells in the CON+NS group were structurally intact, with clear borders and neatly arranged; compared with the CON+NS group, the hippocampal cells in the MS+NS groupwere structurally indistinct, poorly arranged and lax, with lysis and destruction, and the expression of 5-HT, cAMP, CREB, and BDNF was not obvious; compared with the MS+NS group, the MS+P group had relatively intact hippocampal cell edges, relatively neat arrangement, clearer structure, lysis and destruction, increased cell numbers, and more obvious expression of 5-HT,cAMP, CREB, and BDNF. Figure 8.