Figure 2 The open field experiment (n=12). (A) indicates the centraltime of each group of rats in the open-field experimental test; (B) indicates the central activity distance of each group of rats in the open-field experimental test; (C) indicates the total distance of each group of rats in the open-field experimental test; (D) indicates the schematic diagram of the trajectory of each group in the open-field experiment.
Note: *P <0.05 and **P <0.01 compared with the CON+NS group;#P <0.05 and##P <0.01 compared with the MS+NS group.
3.1.3 Effect of probiotics on forced swimming experiment in mother-infant separated offspring of depressed-like rats
Forced swimming experiment tests immobilization time to reflect desperate behavior in rodents[46], The results showed that the floating immobility time was increased in the MS+NS group compared with the CON+NS group, and the difference was statistically significant (P <0.01); the floating immobility time was decreased in the MS+P group compared with the MS+NS group, and the difference was statistically significant (P <0.01); there was no significant change in the floating immobility time of rats in the CON+NS group compared with the MS+P group (P >0.05).Figure 3.