Figure 4. Cooperativity of NRF2 with ATF4 and CEBPB.
Functional cooperativity of NRF2 with ATF4 and CEBPB occurs in cancer cells with constitutive activation of NRF2. Gene categories shown in red are canonical NRF2 target genes. Gene categories shown in green and blue are regulated under the regulation by NRF2-ATF4 and NRF2-CEBPB cooperativity, respectively.