Highlights
- Substantial waning of the humoral response was observed 6 months after
the bivalent booster administration, especially considering the
XBB.1.5 subvariant.
- A significant decay in the cellular response was also observed over
time.
- The proportion of samples still able to release IFNγ in response to anin vitro SARS-CoV-2 stimulation remained however
high.