Introduction
Epithelial–myoepithelial carcinoma (EMC) is a rare salivary gland
neoplasm with an incidence of <1% among all salivary gland
tumors.1 EMC has a biphasic appearance with ductal
epithelial and myoepithelial cells and a wide spectrum of histological
appearances; therefore, it is often difficult to diagnose. HRASmutations are a frequent genetic alteration in EMC2;
however, few published reports have used the detection of HRASmutations for diagnostic purposes. Herein, we describe two cases of EMC
in which genetic testing revealed an HRAS mutation.