2.1 Study population
This is a retrospective study of fetuses with d-TGA, for which fetal
echocardiography was performed at our tertiary hospital from January
2018 to May 2023. In this cohort, we included fetuses diagnosed with
d-TGA on the second trimester ultrasonographic screening or referred to
our hospital for confirmation of the diagnosis. Exclusion criteria
included fetuses with congenitally corrected TGA, double-inlet left
ventricle, atrioventricular septal defect, atrioventricular valve
atresia, great artery stenosis-atresia, or any extracardiac anomaly.
Fetuses with additional cardiac and non-cardiac anomalies were also
excluded because they might adversely affect the postnatal hemodynamic
status. Ventricular septal defects (VSD) were not considered a major
cardiac anomaly. We only enrolled cases in which the last prenatal
echocardiographic examination was performed within two weeks prior to
delivery and whose ultrasonographic videos and images were available.
The study was approved by the ethics committee of Zeynep Kamil Women and
Children Diseases Training and Research Hospital (Date and number:
24.05.2023/87) and was performed in compliance with the Declaration of
Helsinki. Data retrieval and reporting conformed to the Strengthening
the Reporting of Observational Studies in Epidemiology (STROBE)
checklist.