2.1 Study population
This is a retrospective study of fetuses with d-TGA, for which fetal echocardiography was performed at our tertiary hospital from January 2018 to May 2023. In this cohort, we included fetuses diagnosed with d-TGA on the second trimester ultrasonographic screening or referred to our hospital for confirmation of the diagnosis. Exclusion criteria included fetuses with congenitally corrected TGA, double-inlet left ventricle, atrioventricular septal defect, atrioventricular valve atresia, great artery stenosis-atresia, or any extracardiac anomaly. Fetuses with additional cardiac and non-cardiac anomalies were also excluded because they might adversely affect the postnatal hemodynamic status. Ventricular septal defects (VSD) were not considered a major cardiac anomaly. We only enrolled cases in which the last prenatal echocardiographic examination was performed within two weeks prior to delivery and whose ultrasonographic videos and images were available.
The study was approved by the ethics committee of Zeynep Kamil Women and Children Diseases Training and Research Hospital (Date and number: 24.05.2023/87) and was performed in compliance with the Declaration of Helsinki. Data retrieval and reporting conformed to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist.