Study Limitations
There were some limitations identified in this systematic review and meta-analysis. Firstly, the severity of the disease in the patients included from the included studies were variable which may potentially impact test performances. Secondly, strain assessment reported in the included studies were all acquired using four different vendor-specific software, which may potentially also impact the external validity of 2D LV-GLS across different settings. Thirdly, different aetiologias of myocarditis were included which can also bias the overall results. Lastly, the included studies were all single-centre studies, which are typically limited by greater inherent bias due to the greater variation and generalisability between diagnostic work-up and protocols between different centres in different studies. However, we did assess for potential small-study effects on the individual parameters studied using Egger’s tests which did not demonstrate any evidence of small study effects confounding the results.