CONCLUSIONS
This systematic review and meta-analysis demonstrated the discriminatory
value of a range of echocardiographic parameters, particularly with
LV-GLS, in discriminating acute myocarditis from normal controls and
highlights the potential value of early TTE in suspected cases of
myocarditis. However, there is also clearly a need for further large
multi-centre studies or randomized controlled trials to further
characterize the sensitivity and specificity of each of the individual
parameters assessed. Nonetheless, these results support the importance
of echocardiography as an initial non-invasive diagnostic tool for the
work-up of such populations.
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