Comparison of TLS occurrence between datasets of lymphoma patients
To assess the occurrence of TLS, we conducted a comparative analysis of our cohort with other datasets. Firstly, we examined the Swiss Burkitt lymphoma (BL) dataset consisting of 20 cases [19] (Table 4A). In our cohort, which included 13 cases of BL, no CTLS cases were observed, while four cases of LTLS were documented. In the Swiss BL dataset, CTLS was reported in 5% (1 out of 20 cases), and information regarding LTLS occurrence was not available. Additionally, we compared patients with DLBCL from our cohort (n=78) with the CALGB 50303 (NCT0011820) dataset comprising 473 patients. Within our cohort, one CTLS case (1.3%) and two LTLS cases were identified. In the CALGB 50303 dataset, CTLS occurred in 0.85% of patients (Table 4B), while no information regarding LTLS cases was reported.