Comparison of TLS occurrence between datasets of lymphoma
patients
To assess the occurrence of TLS, we conducted a comparative analysis of
our cohort with other datasets. Firstly, we examined the Swiss Burkitt
lymphoma (BL) dataset consisting of 20 cases [19] (Table 4A). In our
cohort, which included 13 cases of BL, no CTLS cases were observed,
while four cases of LTLS were documented. In the Swiss BL dataset, CTLS
was reported in 5% (1 out of 20 cases), and information regarding LTLS
occurrence was not available. Additionally, we compared patients with
DLBCL from our cohort (n=78) with the CALGB 50303 (NCT0011820) dataset
comprising 473 patients. Within our cohort, one CTLS case (1.3%) and
two LTLS cases were identified. In the CALGB 50303 dataset, CTLS
occurred in 0.85% of patients (Table 4B), while no information
regarding LTLS cases was reported.