Fig. 6. PHI inhibited the inflammation of BMDMs by inhibiting the NLRP3 inflammasome pathway. (A) The cell viability of BMDM with PHI treatment. (B and C) The protein and gene expression levels in LPS-induced BMDM. (D) The gene expression level of Nlrp3 and Caspase 1. (E) The protein expression of inflammasome and its upstream pathway. (F) Representative images of immunofluorescence staining of NLRP3, bar = 10 μm. Compared with the LPS or LPS&ATP-stimulated group *p <0.05, **p <0.01, ***p <0.001, n = 3-4.