The predictive of Th17/Treg ratio, SOFA score, APACHE II score
on length of ICU stay
The limited data suggested the ratio of Th17/Treg predicted the length
of septic patient ICU stay. The area under the ROC curve(AUC)of the
Th17/Treg ratio, SOFA score and APACHE II score was 0.747(95%CI:
0.618-0.850), 0.764(95%CI: 0.637-0.864) and 0.760(95%CI: 0.6333-0.861)
respectively for ICU stay more than 14 days. Combined either SOFA score
or APACHE Ⅱ score with the ratio of Th17 / Treg, although there is no
statistically difference each other, but its AUC of predictive value on
the length of sepsis patients’ ICU stay is higher, with AUC value of
0.782 (95% CI: 0.656-0.878) or 0.800 (95% CI: 0.676-0.892). The
sensitivity and specificity for predicting ICU stay based on cut-off
values are shown in Figure 3.