Mouse clinical score after treatment.
After CLP-induced polymicrobial sepsis successfully in mice, all of them
moved free and none needed analgesia for pain immediately. The clinical
scores of mice at 0h, 2h, 6h, 12h, 24h, 48h, 72h, 4d, 5d and 7d by
incorporating to the Murine Sepsis Score (MSS) were evaluated. The
scoring criteria are as follows: spontaneous activity, response to touch
and auditory stimuli, posture, respiration rate and quality (labored
breathing or gasping), and appearance (i.e., degree of piloerection),
each of these scores variables between 0-4[22].