Introduction: In this study, we aimed to investigate cardiac involvement in patients diagnosed with the new Coronavirus Disease 2019 (COVID-19). Materials and Methods: Patients diagnosed with COVID-19 pneumonia in the emergency department were included in this retrospective study. Patients diagnosed with COVID-19 pneumonia were included in Group 1 and healthy individuals (as control group) were included in Group 2.CCT images were transferred to the Intrasense Myrian® software. Total cardiac volume (TCV) was measured in three-dimensional images. Obtained parameters were compared between groups Results: Total cardiac volume was 525.35±29.96 cm3 (min:244cm3 - max:1545cm3) in Group 1 and 369.64±10.41cm3 (min:229cm3 - max:522cm3) in Group 2 (P=0.000). In Group 1 patients, levels of D-dimer, C-reactive protein (CRP) and high sensitivity troponin I (hs-TnI) were 391.00 (6.00-6450) µg/L, 3.50 (0.10-30.40) mg/dL and 4.41 (1.00-3627.00) ng/mL, respectively, whereas those in Group 2 were 112.50 (3.00-767.00) µg/L, 0.20 (0.10-19.30) mg/dL and 2.50 (2.30-36.02) ng/mL, respectively (P<0.05). Conclusion: Total cardiac volume increases in patients that develop pneumonia due to COVID-19 infection. D-dimer, CRP and hs-TnI levels also increase with TCV. Keywords: COVID-19, chest computed tomography, total cardiac volume, C-reactive protein, D-dimer, high sensitive troponin I