Abstract
A thirty-eight year-old male presented with a seven-week history of
persistent fever accompanied by recurrent night sweats, chills,
arthralgias, headache, and chest tightness. Initial laboratory testing
showed non-specific elevation of inflammatory markers, but was otherwise
unremarkable. A palmar rash developed one week later, prompting testing
for syphilis. Fluorescent treponemal antibody absorption (FTA-ABS) and
rapid plasma reagin (RPR) tests were both positive. Penicillin G was
administered and the patient recovered uneventfully. Our case emphasizes
the need for increased syphilis screening to ensure proper diagnosis and
prompt treatment.